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1200 Series Rapid Resolution LC System

Secure performance on the fastest, most efficient and most flexible LC in the world!

Rapid Resolution LC (RRLC) on the new Agilent 1200 Series Rapid Resolution LC System (1200 RRLC System) provides up to 20 times faster analysis and 60 % higher resolution than conventional HPLC without sacrificing resolution, precision or sensitivity. While pushing performance to new limits the system can still run any traditional HPLC method without compromise. Further, a special high-throughput configuration allows sequential execution of 2,000 samples per day on a single system - all without giving up data quality or method flexibility.

The system features more than 70 new Rapid Resolution High Throughput (RRHT) columns and a new high-performance pump that can handle flow rates from 0.05 to 5 mL/min at up to 600 bar pressure and offers a configurable delay volume for optimized support of narrow and standard bore columns. It also features a new high-performance degasser, autosampler, column compartment and high-speed detectors.

The Agilent 1200 Series Rapid Resolution LC System was designed to provide highest analysis speed and resolution while keeping system pressure at a minimum. As a consequence it maintains the robustness and operating principles known from conventional HPLC instruments and methods. The unique design makes the 1200 RRLC a universal LC for the analytical flow rate range with column dimension from 1 to 4.6-mm ID, 10 to 300-mm length and particle sizes from 1.5 to 10 µm.

Features and Benefits

  • Up to 20x faster than conventional HPLC with same or better data quality (resolution, sensitivity, precision)
  • 60 % higher resolution compared to HPLC with same or better data quality (resolution, sensitivity, precision)
  • Configurable delay volume for universal applicability by uncompromised support of narrow and standard bore columns - both RRLC and HPLC
  • Uncompromised compatibility with existing HPLC methods using column length up to 300 mm by standard delay volume configuration (600 - 800 µL)
  • Optimum support of LC/MS on narrow bore columns by low delay volume configuration (120 µL)
  • Compliant with strictest regulatory performance requirements
  • Broad range of more than 70 RRHT columns for wide applicability
  • Easy, fast and secure method transfer from HPLC to RRLC by identical column chemistry of RRHT and HPLC columns
  • 2000 samples/day on high throughput configuration, with Alternating Column Regeneration (ACR) using system setup with two pumps, two columns and a 2Ps/10Pt valve for alternating column switching.
  • Modular, scalable and open system offers future expandability and adaptability
  • Compatibility with Agilent 1100 Series modules allows stepwise transition to full RRLC capabilities
  • Agilent 1100 Sereis emulation mode allows to run the Agilent 1200 Sereis RRLC system under 3rd party software that does not offer 1200 control yet, but 1100 control only.
  • Agilent Intelligent Services for remote performance and utilization monitoring and predictive maintenance.
  • "Data never lost insurance" by built-in data recovery card (DRC) prevents data losses in case of communication breakdowns between instrument and PC (1200 Series DAD SL and 1200 Sreis MWD SL)
  • Improved data traceability by RFID tags for all flow cells and UV lamp record parameters like flow cell dimensions, lamp usage and product/serial number and save them with raw data file.
  • Full compliance by new and flexible Automated Compliance Engine (ACE)
| Agilent 1200 LC | Agilent 1200 RR | Agilent 6210 | Agilent 6300 |
| Agilent 6410 | Agilent 6510 | Agilent |
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